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Resources for You and Your Family

As part of our ongoing support, we have provided some helpful resources about Alnylam Assist® and treatment with GIVLAARI™ (givosiran). In addition, we’ve included some organizations that provide community support and educational materials for those affected by acute hepatic porphyria (AHP).

Downloadable Resources

Alnylam Assist® - Downloadable PDF

Alnylam Assist® Brochure

Download

Alnylam Assist® - Downloadable PDF

GIVLAARI Brochure

Download

Alnylam Assist® - Downloadable PDF

GIVLAARI Prescribing Information

Download

Disease and Advocacy Resources

American Porphyria Foundation

American Porphyria Foundation

The American Porphyria Foundation focuses on porphyria education, advocacy, support services, and research.

www.porphyriafoundation.org

National Organization for Rare Disorders

The National Organization for Rare Disorders offers educational videos and interactive webinars along with a variety of additional resources.

www.rarediseases.org

Global Genes

Global Genes is your ally in the fight against rare disease. Global Genes provides helpful resources while sponsoring local and global events to help connect, empower, and inspire the rare disease community.

www.globalgenes.org

How do I get started with Alnylam Assist®?

To get started, you must be prescribed GIVLAARI and fill out the Start Form with your doctor. Once the form is completed and you’ve signed it, your doctor can submit the form online or print it out and fax it to Alnylam Assist®. Find out how to get started ›

Alnylam Assist® - FAQ

Find answers to other

Frequently Asked Questions ›

Alnylam Assist™ get started icon

See How to Get Started

Once you and your healthcare team decide to begin treatment with GIVLAARI, we'll work with them to start the process.

How to Get Started

Call Shontae

1-833-256-2748

Monday - Friday, 8am - 6pm ET

Alylam Separator Triangles

IMPORTANT SAFETY INFORMATION

Do not use GIVLAARITM (givosiran) if you have ever had a severe allergic reaction to GIVLAARI.

GIVLAARI can cause:

Severe allergic reaction

Tell your doctor or nurse right away if you experience any of the following signs or symptoms of a severe allergic reaction during treatment:

Swelling – mainly of the lips, tongue or throat which makes it difficult to swallow or breathe
  Breathing problems or wheezing
  Feeling dizzy or fainting
  Rash or hives
  Itching

If you have a severe allergic reaction, your doctor or nurse will stop using GIVLAARI treatment right away and you may need to take other medicines to control the symptoms.

Liver problems

Your doctor will check your liver function by doing blood tests:

Before you start using GIVLAARI
  Once a month for the first 6 months of treatment
  And when they think it is needed

If these tests show abnormal results, your doctor or nurse will decide whether to temporarily interrupt or stop treatment with GIVLAARI.

Kidney problems

Your doctor will check how your kidneys are working while you are using GIVLAARI.

Injection site reactions

GIVLAARI is given as an injection under the skin (called a "subcutaneous injection"). Reactions to this injection may happen during treatment with GIVLAARI.

Tell your doctor or nurse right away if you experience any of the following symptoms of an injection site reaction during treatment: redness, pain, itchiness, rash, discoloration, or swelling around the injection site.

What are the common side effects of GIVLAARI?

The most common side effects of GIVLAARI are nausea and injection site reactions. These are not all the possible side effects of GIVLAARI. Talk to your doctor about side effects that you experience. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What is GIVLAARI?

GIVLAARI is a prescription medicine used to treat acute hepatic porphyria (AHP) in adults.

For additional information about GIVLAARI, please see full Prescribing Information.