Alnylam Assist® Case Managers Support
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Alnylam Assist® knows how important one-on-one interactions are, which is why we have dedicated Case Managers and Patient Education Liaisons (PELs) for each patient to provide ongoing education, tools to connect with the community, and resources that can help you during treatment.

Alnylam Assist™ Case Managers

Case Managers

Once you and your doctor choose to start treatment with GIVLAARI® (givosiran), you will be partnered with a dedicated Alnylam Case Manager. Case Managers are trained professionals whose expertise is in helping patients get started on treatment and providing ongoing support. They will tailor their level of contact based on your personal needs.

Your Case Manager will give you an understanding of your insurance coverage benefits and verify them for you. They can also assist you with options for financial support that you may be eligible for as well as provide you with educational resources. In addition, Case Managers can connect you with a PEL by request.

Alnylam Assist™ Case Managers

Patient Education Liaisons

Your Case Manager also can help connect you with a Patient Education Liaison (PEL). PELs have backgrounds in nursing and genetic counseling, and are experienced in educating people and their families about matters related to AHP. Your PEL can help you in a variety of ways, such as:

Supporting you with disease education

Providing you with product information

Connecting you to additional resources

Answering questions about treatment with GIVLAARI

In addition, PELs help facilitate educational events about AHP in communities around the United States. Talk to your Case Manager about finding an event in your area, or request a conversation with a PEL. Talk to a PEL ›

Alnylam Assist Dedicated Case Manager

Meet Your Case ManagerRead Shontae's Bio ›

What additional resources does Alnylam Assist® offer?

Downloadable educational materials about AHP and GIVLAARI treatment, as well as links to advocacy groups that connect patients to the AHP community are available. Find additional resources ›

Alnylam Assist® - FAQ

Find answers to other

Frequently Asked Questions ›

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See How to Get Started

Once you decide to begin treatment with GIVLAARI, we'll work with your healthcare team to start the process.

How to Get Started

Alnylam Assist® Case Manager Shontae

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Monday - Friday, 8am - 6pm ET

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Do not use GIVLAARI® (givosiran) if you have ever had a severe allergic reaction to GIVLAARI.

GIVLAARI can cause:

Severe allergic reaction

Tell your doctor or nurse right away if you experience any of the following signs or symptoms of a severe allergic reaction during treatment:

Swelling – mainly of the lips, tongue or throat which makes it difficult to swallow or breathe
  Breathing problems or wheezing
  Feeling dizzy or fainting
  Rash or hives

If you have a severe allergic reaction, your doctor or nurse will stop GIVLAARI treatment right away and you may need to take other medicines to control the symptoms.

Liver problems

Your doctor will check your liver function by doing blood tests:

Before you start using GIVLAARI
  Once a month for the first 6 months of treatment
  And when they think it is needed

If these tests show abnormal results, your doctor or nurse will decide whether to temporarily interrupt or stop treatment with GIVLAARI.

Kidney problems

Your doctor will check how your kidneys are working while you are using GIVLAARI.

Injection site reactions

GIVLAARI is given as an injection under the skin (called a "subcutaneous injection"). Reactions to this injection may happen during treatment with GIVLAARI.

Tell your doctor or nurse right away if you experience any of the following symptoms of an injection site reaction during treatment: redness, pain, itchiness, rash, discoloration, or swelling around the injection site.

What are the common side effects of GIVLAARI?

The most common side effects of GIVLAARI are nausea and injection site reactions. These are not all the possible side effects of GIVLAARI. Talk to your doctor about side effects that you experience. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.


GIVLAARI is a prescription medicine used to treat acute hepatic porphyria (AHP) in adults.

For additional information about GIVLAARI, please see full Prescribing Information.