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Resources for You and Your Family

As part of our ongoing support, we have provided some resources about Alnylam Assist™ and treatment with ONPATTRO® (patisiran). In addition, we’ve included some organizations that provide community support and educational materials for those affected by hereditary ATTR (hATTR) amyloidosis.

Your Team at a Glance

Alnylam Assist® Case Managers

After you begin treatment and enroll in Alnylam Assist™, your dedicated Case Manager, a Patient Education Liaison (PEL), and the Alnylam Assist™ team will provide ongoing one-on-one support and education in 3 key areas:

Understanding Benefits

Financial Options

Disease and Treatment

Alnylam Assist® - Downloadable PDF

Alnylam Assist™ Brochure

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Alnylam Assist™ FAQs

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ONPATTRO® Resources

Explore the resources below to learn about treatment with ONPATTRO.

Alnylam Assist® - Downloadable PDF

ONPATTRO® (patisiran) Brochure

This brochure helps educate and inform you and your loved ones about hATTR amyloidosis, describes how the polyneuropathy of hATTR amyloidosis affects your body, and shows results from an ONPATTRO clinical study.

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Insurance Resources

Alnylam Assist™ provides insurance benefit guidance and resources
to help support patients throughout treatment.

99%

of patients receiving treatment with ONPATTRO are enrolled in Alnylam Assist

$0

out-of-pocket cost for ONPATTRO for patients enrolled in Alnylam’s Commercial Copay Program

98%

of U.S. lives have confirmed access to ONPATTRO across commercial, Medicare, Medicaid, and other government payer categories*

  Patients must meet specified criteria to qualify for assistance. Alnylam reserves the right to make eligibility determinations and to modify or discontinue the program at any time.

*  Coverage may vary for individual and plan. Data as of [March 2021].

Alnylam Assist® - Downloadable PDF

Explanation of Benefits (EOB)

This sheet outlines insurance company EOBs, what information they contain, and how to better understand them.

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Alnylam Assist® - Downloadable PDF

Glossary of Insurance Terms

A handy reference glossary to help educate patients and caregivers about common insurance terminology.

Download PDF

Alnylam Assist® - Downloadable PDF

Young Adult Transitions Brochure

Young adult patients with rare diseases who are transitioning to their own insurance have important decisions to make. This brochure covers the most important aspects of changing insurance plans.

Download PDF

Caregiver Resources

Caregivers of people with hATTR amyloidosis can play a vital role in helping successfully support their loved ones throughout treatment. Caregiver resources are designed to help these important individuals.

Alnylam Assist® - Downloadable PDF

Alnylam Assist™ Caregiver Brochure

This brochure was designed to support caregivers of patients with rare diseases by offering best practices and tips on how to talk to the healthcare team and provide self care.

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Disease and Advocacy Resources

Amyloidosis Support Groups Logo

Amyloidosis Support Groups

A website dedicated to support groups for those suffering from amyloidosis and other amyloidosis-related diseases.

www.amyloidosissupport.org

Amyloidosis Foundation Logo

Amyloidosis Foundation

Foundation whose priorities include raising awareness, educating medical professionals, and empowering patients affected by amyloidosis.

www.amyloidosis.org

Amyloidosis Research Consortium Logo

Amyloidosis Research Consortium

The Amyloidosis Research Consortium is accelerating the development of effective treatments for systemic amyloidosis through key research, collaboration, and innovation.

www.arci.org/map

National Organization for Rare Disorders Logo

National Organization for Rare Disorders

The National Organization for Rare Disorders offers educational videos and interactive webinars along with a variety of additional resources.

www.rarediseases.org

Foundation for Peripheral Neuropathy Logo

The Foundation for Peripheral Neuropathy

A public charity foundation that strives to cure painful neuropathies through collaborative research, education, and treatment.

www.foundationforpn.org

Global Genes Logo

Global Genes

Global Genes is your ally in the fight against rare disease. Global Genes provides helpful resources while sponsoring local and global events to help connect, empower, and inspire the rare disease community.

www.globalgenes.org

For Caregivers

Caregiver Action Network Logo

Caregiver Action Network (CAN)

The Caregiver Action Network is the nation's leading family caregiver organization working to improve quality of life for the more than 90 million Americans who care for their loved ones.

www.caregiveraction.org

National Alliance for Caregiving Logo

National Alliance for Caregiving (NAC)

The National Alliance for Caregiving is a non-profit coalition dedicated to improving quality of life for friend and family caregivers and those in their care, by advancing research, advocacy, and innovation.

www.caregiving.org

How do I get started with Alnylam Assist™?

To get started, you must be prescribed ONPATTRO and fill out the Start Form with your doctor. Once the form is completed and you’ve signed it, your doctor can submit the form online or print it out and fax it to Alnylam Assist™. Find out how to get started ›

Alnylam Assist® - FAQ

Find answers to other

Frequently Asked Questions ›

Alnylam Assist® get started icon

See How to Get Started

Once you and your doctor decide to begin treatment with ONPATTRO, we'll work with your healthcare team to start the process.

How to Get Started

Alnylam Assist® Case Manager Natalie

Call Natalie

1-833-256-2748

Monday - Friday,
8am - 6pm ET

Alylam Separator Triangles

IMPORTANT SAFETY INFORMATION

What are the most important things I should know about ONPATTRO® (patisiran)?

ONPATTRO can cause:

Infusion-related reactions

ONPATTRO is given as a drip into a vein (called an “intravenous infusion”). Reactions to this infusion may happen during treatment with ONPATTRO. Before each infusion you will be given medicines that help to lower the chance of infusion-related reactions.

Tell your doctor or nurse right away if you experience any of the following signs of an infusion-related reaction during treatment:

Reddening of the face or body (flushing), skin warm
  Body aches or pain, including pain in the back, neck, or joints
  Feeling sick (nausea)
  Stomach pain
  Feeling short of breath, cough, or other breathing problems
  Headache
  Chest discomfort or chest pain
  Rash
  Chills
  Dizziness
  Feeling tired (fatigue)
  Rapid heart rate
  Facial swelling

If you have an infusion-related reaction, your doctor or nurse may slow down or stop your infusion, and you may need to take other medicines. When these reactions stop, or get better, your doctor or nurse may decide to start the infusion again.

Low Vitamin A levels

Treatment with ONPATTRO lowers the amount of vitamin A in your blood. Your doctor will tell you to take a vitamin A supplement every day. You should not take more than the amount of vitamin A recommended by your doctor.

Low vitamin A levels can affect vision. If you have problems with your vision (e.g., night blindness) while taking ONPATTRO, talk to your doctor. Your doctor may refer you to an eye specialist.

What are the common side effects of ONPATTRO?

The most common side effects of ONPATTRO are respiratory infections, such as colds, sinus infections, and nasal congestion, and infusion-related reactions. These are not all the possible side effects of ONPATTRO. Talk to your doctor about side effects that you experience. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

INDICATION

What is ONPATTRO?

ONPATTRO is a prescription medicine that treats the polyneuropathy caused by an illness called hereditary transthyretin-mediated amyloidosis (hATTR amyloidosis). ONPATTRO is used in adults only.

For additional information about ONPATTRO, please see the full Prescribing Information.