Alnylam Assist® Case Managers Support
am -
pm ET

We Are Here to Support You

Alnylam Assist® is committed to providing truly personalized support. You will have your own dedicated Case Manager to help you have a smooth treatment experience with GIVLAARI® (givosiran) and answer questions you may have along the way. It’s the support you need, when you need it.

Alnylam Assist® - Understanding Insurance Benefits
Understanding Insurance Benefits

Your Case Manager will thoroughly review your insurance coverage to verify benefits and help you access GIVLAARI. We encourage you to call your Case Manager with any questions you may have on an ongoing basis.

Alnylam Assist® - Financial Assistance
Financial Assistance Options

Alnylam provides assistance options for qualifying individuals. Your Case Manager will work with you to determine eligibility.*

Quick Start Program

Copay Program

Patient Assistance Program

*  Individuals must meet specified criteria to qualify for assistance. Alnylam reserves the right to make eligibility determinations and to modify or discontinue the program at any time.

Alnylam Assist® - Disease And Treatment Education
Disease and Treatment Education

Disease education can help you and your loved ones make more informed choices about your health. Your Case Manager can connect you with a Patient Education Liaison (PEL), a trained individual who can directly answer questions about acute hepatic porphyria (AHP) and treatment with GIVLAARI, and provide resources and information to help you and your family learn more about this condition.

Introduction to Alnylam Assist®

Watch this video to see all that Alnylam Assist® has to offer.
Alnylam Assist® - Introduction Video
I’m in the patients’ corner, supporting them through challenging times. That’s why I strive to go above and beyond to service those in need.


Renae, Case Manager

Resources for You

Alnylam Assist® - Downloadable PDF

Download the Alnylam Assist® Brochure


Alnylam Assist® - Downloadable PDF

Download the GIVLAARI® (givosiran) Brochure


Who can support me with the Alnylam Assist® program?

When you and your doctor choose to begin treatment with GIVLAARI, you will have a personal Case Manager and access to a Patient Education Liaison (PEL). Meet your Alnylam Assist® team ›

Alnylam Assist® - FAQ

Find answers to other

Frequently Asked Questions ›

Alnylam Assist® get started icon

See How to Get Started

Once you decide to begin treatment with GIVLAARI, we'll work with your healthcare team to start the process.

How to Get Started

Alnylam Assist® Case Manager Shontae

Call Shontae


Monday - Friday, 8am - 6pm ET

Alylam Separator Triangles


Do not use GIVLAARI® (givosiran) if you have ever had a severe allergic reaction to GIVLAARI.

GIVLAARI can cause:

Severe allergic reaction

Tell your doctor or nurse right away if you experience any of the following signs or symptoms of a severe allergic reaction during treatment:

Swelling – mainly of the lips, tongue or throat which makes it difficult to swallow or breathe
  Breathing problems or wheezing
  Feeling dizzy or fainting
  Rash or hives

If you have a severe allergic reaction, your doctor or nurse will stop GIVLAARI treatment right away and you may need to take other medicines to control the symptoms.

Liver problems

Your doctor will check your liver function by doing blood tests:

Before you start using GIVLAARI
  Once a month for the first 6 months of treatment
  And when they think it is needed

If these tests show abnormal results, your doctor or nurse will decide whether to temporarily interrupt or stop treatment with GIVLAARI.

Kidney problems

Your doctor will check how your kidneys are working while you are using GIVLAARI.

Injection site reactions

GIVLAARI is given as an injection under the skin (called a "subcutaneous injection"). Reactions to this injection may happen during treatment with GIVLAARI.

Tell your doctor or nurse right away if you experience any of the following symptoms of an injection site reaction during treatment: redness, pain, itchiness, rash, discoloration, or swelling around the injection site.

What are the common side effects of GIVLAARI?

The most common side effects of GIVLAARI are nausea and injection site reactions. These are not all the possible side effects of GIVLAARI. Talk to your doctor about side effects that you experience. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.


GIVLAARI is a prescription medicine used to treat acute hepatic porphyria (AHP) in adults.

For additional information about GIVLAARI, please see full Prescribing Information.