Alnylam Assist™: Patient Support Program

Hi, I’m Natalie

Your Local Case Manager

I'm here to support patients throughout their Alnylam treatment experience. I am specifically assigned to work with certain patients on questions they may have about Alnylam Assist™ and AMVUTTRA© (vutrisiran).

Call Natalie:


Monday - Friday,
8am - 6pm

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How We Can Help

Now that you or your loved one have been prescribed AMVUTTRA, Alnylam Assist™ is here to help you access therapy.

Each person is unique - support should be that way too. Alnylam Assist™ will adapt to your needs based on where you are on the treatment journey and will tailor their method of communication to what works best for you.

How We Can Help

Support to Get Started

After you begin treatment with AMVUTTRA and enroll, Alnylam Assist™ will provide product support in 3 key areas:

Alnylam Assist® - Understanding Your Benefits
Understanding Your Benefits

Review and verify your insurance benefit coverage for AMVUTTRA treatment.

Alnylam Assist™ - Financial Assistance Options
Financial Assistance

Alnylam Assist™ provides financial assistance options for qualifying individuals. An Alnylam Case Manager will work with you to determine eligibility.*

*  Patients must meet specified eligibility criteria to qualify for assistance. Alnylam reserves the right to make eligibility determinations and to modify or discontinue any program at any time.

Alnylam Assist® - Disease And Treatment Education
Disease and Product Education

Materials to help educate you and your family on hATTR amyloidosis and treatment.

Support for Your Journey

Alnylam Assist™ can help educate you and your loved ones about hATTR amyloidosis and connect you with advocacy organizations that are involved in the hATTR amyloidosis community.

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Our Message to Caregivers

Alnylam Assist™ Caregiver Support Icon

We understand that hATTR amyloidosis can affect more than just one individual

Alnylam Assist is here to help your loved one access AMVUTTRA® (vutrisiran) and can provide you with additional resources to learn more about the disease and treatment.

See More Resources

Alnylam Assist® get started icon

See How to Get Started

Once you and your doctor decide to begin treatment with AMVUTTRA, we'll work with your healthcare team to start the process.

How to Get Started

Alnylam Assist® Case Manager Natalie

Call Natalie


Monday - Friday,
8am - 6pm

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What are the most important things I should know about AMVUTTRA® (vutrisiran)?

AMVUTTRA can cause:

Low Vitamin A Levels

Treatment with AMVUTTRA lowers the amount of vitamin A in your blood. Your doctor will tell you to take a vitamin A supplement every day. You should not take more than the amount of vitamin A recommended by your doctor.

Low vitamin A levels can affect vision. If you have problems with your vision (e.g., night blindness) while taking AMVUTTRA, talk to your doctor. Your doctor may refer you to an eye specialist.

What are the common side effects of AMVUTTRA?

The most common side effects of AMVUTTRA are pain in the joints (arthralgia), shortness of breath (dyspnea), and low vitamin A levels.

These are not all the possible side effects of AMVUTTRA. Talk to your doctor about side effects that you experience. You are encouraged to report negative side effects of prescription drugs to the U.S. Food and Drug Administration (FDA). Visit, or call 1-800-FDA-1088.


What is AMVUTTRA® (vutrisiran)?

AMVUTTRA is a prescription medicine that treats the polyneuropathy caused by an illness called hereditary transthyretin‑mediated amyloidosis (hATTR amyloidosis). AMVUTTRA is used in adults only.

For additional information about AMVUTTRA, please see the full Prescribing Information.