Alnylam Assist® Case Manager Speaking With Patient

Alnylam Assist®: Support for Every Step


Dedicated Case Managers

We’re here to support you throughout your treatment experience and assist you with any questions you may have about Alnylam Assist® and GIVLAARI™ (givosiran).

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Monday - Friday, 8am - 6pm ET

Get Started

How We Can Help

If you or your loved one has been diagnosed with acute hepatic porphyria (AHP) and has been prescribed GIVLAARI, Alnylam Assist® is here to provide you with customized, ongoing support throughout your treatment.

Alnylam Assist® - Understanding Insurance Benefits
Understanding Your Benefits

Your Case Manager will review your insurance coverage and answer any questions about your insurance benefits for GIVLAARI.

Alnylam Assist® - Financial Assistance
Financial Assistance

Alnylam Assist® provides financial assistance options for qualifying individuals. Your Case Manager will work with you to determine eligibility.*

Alnylam Assist® - Disease And Treatment Education
Disease Education

Education can help you make more informed choices about your health. Your Case Manager can connect you with an Alnylam Patient Education Liaison (PEL) who can answer questions about acute hepatic porphyria and provide resources to help you and your family learn more about the condition.

*  Individuals must meet specified criteria to qualify for assistance. Alnylam reserves the right to make eligibility determinations and to modify or discontinue the program at any time.

How to Get Started

When you and your doctor choose to begin treatment with GIVLAARI, the first step is to complete the Start Form together.

Then, your doctor will submit the form to Alnylam Assist®. Upon receipt of the Start Form, your dedicated Alnylam Case Manager will reach out to you and your doctor within 1-2 business days.

Before you begin this process with your doctor, please take a few minutes to review the types of information you will need to fill out for your sections of the Start Form:

Personal Information

Personal Information

This includes basic information like your name, date of birth, current mailing address, email, and phone number.

Primary Insurance Information

Primary Insurance Information

This includes information found on your insurance card, if you have one. You will need your plan name, policy number, and group number, so be sure to have your insurance card available.

Physician Information

Physician Information

In order to get started with Alnylam Assist®, your doctor is required to initiate your enrollment in the program and provide their information.

Alnylam Assist® - Downloadable PDF

Want to learn more about GIVLAARI?

Download the patient brochure


Alnylam Assist® - Downloadable PDF

Do you have questions about AHP?

Fill out the form to request a live call with a Patient Education Liaison.

Coming Soon

Call an Alnylam Assist® Case Manager

Call Us:


Monday - Friday, 8am - 6pm ET

Alylam Separator Triangles


Do not use GIVLAARI (givosiran) if you have ever had a severe allergic reaction to GIVLAARI.

GIVLAARI can cause:

Severe allergic reaction

Tell your doctor or nurse right away if you experience any of the following signs or symptoms of a severe allergic reaction during treatment:

Swelling – mainly of the lips, tongue or throat which makes it difficult to swallow or breathe
  Breathing problems or wheezing
  Feeling dizzy or fainting
  Rash or hives

If you have a severe allergic reaction, your doctor or nurse will stop using GIVLAARI treatment right away and you may need to take other medicines to control the symptoms.

Liver problems

Your doctor will check your liver function by doing blood tests:

Before you start using GIVLAARI
  Once a month for the first 6 months of treatment
  And when they think it is needed

If these tests show abnormal results, your doctor or nurse will decide whether to temporarily interrupt or stop treatment with GIVLAARI.

Kidney problems

Your doctor will check how your kidneys are working while you are using GIVLAARI.

Injection site reactions

GIVLAARI is given as an injection under the skin (called a "subcutaneous injection"). Reactions to this injection may happen during treatment with GIVLAARI.

Tell your doctor or nurse right away if you experience any of the following symptoms of an injection site reaction during treatment: redness, pain, itchiness, rash, discoloration, or swelling around the injection site.

What are the common side effects of GIVLAARI?

The most common side effects of GIVLAARI are nausea and injection site reactions. These are not all the possible side effects of GIVLAARI. Talk to your doctor about side effects that you experience. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.


GIVLAARI is a prescription medicine used to treat acute hepatic porphyria (AHP) in adults.

For additional information about GIVLAARI, please see full Prescribing Information.