Alnylam Assist®: Support for Every Step
Hi, I’m Rachael
I'm here to support you throughout your treatment experience and have been specifically assigned to assist you with questions you may have about Alnylam Assist® and GIVLAARI® (givosiran).
Call Rachael:
Monday - Friday, 8am - 6pm ET
How We Can Help
Now that you or your loved one has been diagnosed with acute hepatic porphyria (AHP) and has been prescribed GIVLAARI® (givosiran), Alnylam Assist® is here to help support you.
Each person is unique—your support should be that way, too. Alnylam Assist® is designed to be truly personalized: a support team who is there for you, easy to access, and adaptable. So if your support needs change during treatment, your level of support can change, too.
Get the Support You Need
After you begin treatment with GIVLAARI and enroll in Alnylam Assist®, your dedicated Case Manager and the Alnylam Assist® team will provide ongoing support in 3 key areas:
Understanding Your Benefits
Review and verify your insurance benefit coverage for GIVLAARI treatment.
Financial Assistance Options
Alnylam Assist® provides financial assistance options for qualifying individuals. Your Case Manager will work with you to determine eligibility.*
* Individuals must meet specified criteria to qualify for assistance. Alnylam reserves the right to make eligibility determinations and to modify or discontinue the program at any time.
Disease and Treatment Education
Materials to help educate you and your family on the disease and treatment with GIVLAARI.
Support for Your Journey
In addition to personalized support from your Case Manager, Alnylam Assist® can help educate you and your loved ones about AHP and connect you with advocacy organizations that are involved in the AHP community.
See How to Get Started
Once you decide to begin treatment with GIVLAARI, we'll work with your healthcare team to start the process.
IMPORTANT SAFETY INFORMATION
Do not use GIVLAARI® (givosiran) if you have ever had a severe allergic reaction to GIVLAARI.
GIVLAARI can cause:
• Severe allergic reaction
Tell your doctor or nurse right away if you experience any of the following signs or symptoms of a severe allergic reaction during treatment:
– Swelling – mainly of the lips, tongue or throat which makes it difficult to swallow or breathe
– Breathing problems or wheezing
– Feeling dizzy or fainting
– Rash or hives
– Itching
If you have a severe allergic reaction, your doctor or nurse will stop GIVLAARI treatment right away and you may need to take other medicines to control the symptoms.
• Liver problems
Your doctor will check your liver function by doing blood tests:
– Before you start using GIVLAARI
– Once a month for the first 6 months of treatment
– And when they think it is needed
If these tests show abnormal results, your doctor or nurse will decide whether to temporarily interrupt or stop treatment with GIVLAARI.
• Kidney problems
Your doctor will check how your kidneys are working while you are using GIVLAARI.
• Injection site reactions
GIVLAARI is given as an injection under the skin (called a "subcutaneous injection"). Reactions to this injection may happen during treatment with GIVLAARI.
Tell your doctor or nurse right away if you experience any of the following symptoms of an injection site reaction during treatment: redness, pain, itchiness, rash, discoloration, or swelling around the injection site.
What are the common side effects of GIVLAARI?
The most common side effects of GIVLAARI are nausea and injection site reactions. These are not all the possible side effects of GIVLAARI. Talk to your doctor about side effects that you experience. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
What is GIVLAARI?
GIVLAARI is a prescription medicine used to treat acute hepatic porphyria (AHP) in adults.
For additional information about GIVLAARI, please see full Prescribing Information.