am -
pm ET

We Are Here to Support You

Alnylam Assist is committed to helping you access therapy. You will work with an Alnylam Case Manager to help you have a smooth treatment experience with AMVUTTRA® (vutrisiran) and answer questions you may have along the way.

Alnylam Assist® - Understanding Your Benefits
Understanding Your Benefits

An Alnylam Case Manager will review your insurance coverage and answer questions about your insurance benefits for treatment with AMVUTTRA.

Alnylam Assist® - Financial Assistance Options
Financial Assistancea

Alnylam offers financial assistance programs for eligible patients. After being prescribed an Alnylam product, you can talk to a Case Manager to learn if you may be eligible. Below are examples of two Alnylam Financial Assistance programs.

I have insurance but have concerns about paying for an Alnylam product

Our Commercial Copay Program covers certain out-of-pocket costs for eligible patients with commercial insuranceb


I'm uninsured, or I have insurance but do not have coverage for an Alnylam product

Our Patient Assistance Program may be able to provide you with one of Alnylam's products at no cost if you're eligible

a  Patients must meet specified eligibility criteria to qualify for assistance. Alnylam reserves the right to make eligibility determinations and to modify or discontinue any program at any time.

b  Patients with Medicare, Medicaid, or other government-sponsored insurance are not eligible for the Alnylam Assist™ Commercial Copay Program. Out-of-pocket costs for the administration of Alnylam products will not be covered for patients residing where it is prohibited by law or where otherwise restricted.

Alnylam Assist® - Disease And Treatment Education
Disease and Product Education

A Case Manager can also connect you with an Alnylam Patient Education Liaison (PEL). PELs have backgrounds in nursing and are experienced in educating family members about their disease. PELs can help you in a variety of ways, including providing disease and product education, connecting you to additional resources, and answer questions about treatment with AMVUTTRA.

The purpose of Alnylam PELs is to provide education to patients, their families, and caregivers. PELs are employees of Alnylam Pharmaceuticals. They are not acting as healthcare providers and are not part of your healthcare team. PELs do not provide medical care or advice. All diagnosis and treatment decisions should be made by you and your doctor.

*  PELs are employees of Alnylam Pharmaceuticals. They are not acting as healthcare providers and are not part of your healthcare team.

Introduction to Alnylam Assist™

Watch this video to learn about Alnylam Assist™
Alnylam Assist® - Introduction Video
I’m in the patients’ corner, supporting them through challenging times. That’s why I strive to go above and beyond to service those in need.


Renae, Case Manager

Resources for You

Alnylam Assist® - Downloadable PDF

Download the Alnylam Assist™ Brochure


Alnylam Assist® - Downloadable PDF

Download the AMVUTTRA Patient Brochure


Who can support me with the Alnylam Assist™ program?

When you and your doctor choose to begin treatment with AMVUTTRA, you will be paired with an Alnylam Case Manager in your area and have access to an Alnylam Patient Education Liaison. Learn about these roles. Meet your Alnylam Assist™ team ›

Alnylam Assist® - Questions Icon

Find answers to other

Frequently Asked Questions ›

Alnylam Assist® get started icon

See How to Get Started

Once you and your doctor decide to begin treatment with AMVUTTRA, we'll work with your healthcare team to start the process.

How to Get Started
Alnylam Assist® Case Manager Natalie

Call Natalie


Monday - Friday,
8am - 6pm

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What are the most important things I should know about AMVUTTRA® (vutrisiran)?

AMVUTTRA can cause:

Low Vitamin A Levels

Treatment with AMVUTTRA lowers the amount of vitamin A in your blood. Your doctor will tell you to take a vitamin A supplement every day. You should not take more than the amount of vitamin A recommended by your doctor.

Low vitamin A levels can affect vision. If you have problems with your vision (e.g., night blindness) while taking AMVUTTRA, talk to your doctor. Your doctor may refer you to an eye specialist.

What are the common side effects of AMVUTTRA?

The most common side effects of AMVUTTRA are pain in the joints (arthralgia), shortness of breath (dyspnea), and low vitamin A levels.

These are not all the possible side effects of AMVUTTRA. Talk to your doctor about side effects that you experience. You are encouraged to report negative side effects of prescription drugs to the U.S. Food and Drug Administration (FDA). Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.


What is AMVUTTRA® (vutrisiran)?

AMVUTTRA is a prescription medicine that treats the polyneuropathy caused by an illness called hereditary transthyretin‑mediated amyloidosis (hATTR amyloidosis). AMVUTTRA is used in adults only.

For additional information about AMVUTTRA, please see the full Prescribing Information.