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Resources for Patients and Their Families

We have provided some resources about Alnylam Assist™ and treatment with OXLUMO® (lumasiran). In addition, we’ve included some organizations that provide community support and educational materials for those affected by primary hyperoxaluria type 1 (PH1).

The Team at a Glance

Alnylam Assist® Case Managers

After you and your doctor decide to begin OXLUMO and enroll in Alnylam Assist™, we can provide support in 3 key areas:

Understanding Benefits

Eligibility For Financial Assistance

Disease and Product Education

Alnylam Assist® - Downloadable PDF

Alnylam Assist™ Brochure


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Alnylam Assist™ FAQs

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OXLUMO® Resources

Explore the resources below to learn about treatment with OXLUMO.

Alnylam Assist® - Downloadable PDF

OXLUMO® (lumasiran) Brochure

This brochure helps educate and inform you and your loved ones about PH1, describes how PH1 affects your body, and shows results from an OXLUMO clinical study.

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Insurance Resources

Alnylam Assist™ provides resources to help patients access therapy throughout the treatment journey.


out-of-pocket cost for OXLUMO for patients enrolled in Alnylam’s Commercial Copay Program


of U.S. lives have confirmed access to OXLUMO across commercial, Medicare, Medicaid, and other government payer categories*

  Patients must meet specified criteria to qualify for assistance. Alnylam reserves the right to make eligibility determinations and to modify or discontinue the program at any time. Limitations may apply.

*  This percentage is an approximation. Coverage may vary for individual and plan. Data as of [June 2022]

Alnylam Assist® - Downloadable PDF

Explanation of Benefits (EOB)

This sheet outlines insurance company EOBs, what information they contain, and how to better understand them.

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Alnylam Assist® - Downloadable PDF

Glossary of Insurance Terms

A handy reference glossary to help educate patients and caregivers about common insurance terminology.

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Caregiver Resources

Caregivers of people with PH1 can play a vital role in helping support their loved ones throughout treatment. Caregiver resources are designed to help these important individuals.

Alnylam Assist® - Downloadable PDF

Alnylam Assist™ Caregiver Brochure

This brochure was designed to support caregivers of patients with rare diseases by offering best practices and tips on how to talk to the healthcare team, dealing with young children, and self-care.

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Disease and Advocacy Resources


Global Genes Logo

Global Genes

Global Genes is your ally in the fight against rare disease. Global Genes provides helpful resources while sponsoring local and global events to help connect, empower, and inspire the rare disease community.


National Institute of Diabetes and Digestive and Kidney Diseases

The National Institute of Diabetes and Digestive and Kidney Diseases conducts and supports research on the most common, costly, and chronic conditions.


National Center for Advancing Translational Sciences

The National Center for Advancing Translational Sciences turns observations into approaches and technologies that can help deliver treatments to more people more quickly.


National Kidney Foundation

The National Kidney Foundation is a lifeline for people with kidney disease, enhancing lives through education.


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National Organization for Rare Disorders

The National Organization for Rare Disorders offers educational videos and interactive webinars along with a variety of additional resources.


Oxalosis and Hyperoxaluria Foundation Logo

Oxalosis & Hyperoxaluria Foundation (OHF)

The OHF is dedicated to finding treatments and a cure for all forms of hyperoxaluria, and supports thousands of healthcare professionals, patients, and their families in their fight against this disease.


For Caregivers

Caregiver Action Network (CAN)

The Caregiver Action Network is the nation's leading family caregiver organization working to improve quality of life for the more than 90 million Americans who care for their loved ones.


National Alliance for Caregiving (NAC)

The National Alliance for Caregiving is a non-profit coalition dedicated to improving quality of life for friend and family caregivers and those in their care, by advancing research, advocacy, and innovation.


How do I get started with Alnylam Assist™?

To get started, you must be prescribed OXLUMO and fill out the Start Form with your doctor. Once the form is completed and you’ve signed it, your doctor can submit the form online or print it out and fax it to Alnylam Assist™. Find out how to get started ›

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Find answers to other

Frequently Asked Questions ›

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See How to Get Started

Once you and your doctor decide to begin treatment with OXLUMO, we'll work with your healthcare team to start the process.

How to Get Started

Alnylam Assist® Case Manager Kevin

Call Kevin


Monday - Friday,
8am - 6pm

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The most common side effect of OXLUMO is injection site reaction (redness, swelling, pain, bruising, itching, and discoloration at the site of injection). These are not all the possible side effects of OXLUMO. Talk to your doctor about side effects that you experience. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

OXLUMO has not been studied in pregnant or breastfeeding women. Talk to your doctor about the risk of taking OXLUMO if you are pregnant, plan to become pregnant, are breastfeeding, or plan to breastfeed.


OXLUMO is a prescription medicine for the treatment of primary hyperoxaluria type 1 (PH1) to lower oxalate in urine and blood in children and adults.

For additional information about OXLUMO, please see the full Prescribing Information.